當(dāng)前位置:首頁(yè) > 產(chǎn)品中心 > 抗體/抗原 > 標(biāo)記一抗 > bs-10200R-HRPHRP標(biāo)記的骨形態(tài)發(fā)生抑制蛋白SOST抗體
簡(jiǎn)要描述:Negative regulator of bone growth.Sclerostin (SOST) is a bone morphogenetic protein (BMP) antagonist, leading to the activation of BMP signaling. It negatively regulates the formation of bone by repressing the differentiation and/or function of osteoblasts induced by BMPs. It has been shown that Sclerostin binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity. The noggin-sclerostin protein complex represents a novel mechanism for the fine-tuning of BMP activity in bon
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